One such example is t(7;12) (q36;p13) acute myeloid leukemia (AML) driven by rearrangement and overexpression of the MNX1 gene locus: MNX1-rearranged (MNX1-r) AML is restricted to infants under the age of 2 and carries a high risk of relapse and poor survival (Ragusa et al., 2023). The gene discussed is MNX1; the disease is acute myeloid leukemia.