The ‘mast cells’ affiliation of MNX1-r AML signatures within the haemGx k14 cluster is also likely to reflect a YS EMP-like affiliation (Chia et al., 2023), and is accordingly aligned with MNX1-OE haemGx isolated at 144 hr (Figure 7—figure supplement 1B). This evidence concerns the gene MNX1 and acute myeloid leukemia.