The significantly transposon-targeted genes in our piggyBac screen were essentially distributed across the entire genome (Fig. 1a and Supplementary Table 4), and our screen returned genes with known roles in SCLC, such as Crebbp, Pten, Nfib and Trp73 (refs. 8,28–30; Extended Data Fig. 1f–i). Here, PTEN is linked to small cell lung carcinoma.