The mRNA and protein expression levels of the carnitine transporter SLC22A16, also known as CT2, necessary for the transport of carnitine into the cytosol, are significantly higher in APL blasts: SLC22A16 mRNA (APL: 57 ± 27, n = 17; AML 17 ± 15, n = 43, p = 0.0001) (Fig. 4C left); SLC22A16 protein (APL: 1.2 ± 0.48), n = 15; AML: 0.7 ± 0.3, n = 13, p = 0.04; NBM 0.1 ± 0.03, n = 3, p = 0.03 (Fig. 4C right). Here, SLC22A16 is linked to acute myeloid leukemia.