Similar results, indicating the inhibition of glycolysis by AKT in APL cells, were obtained using NB4 cells, a cell line derived from a PML::RARα positive APL patient (Fig. 2C), and in PR9 cells induced to express PML::RARα by ZnSO4 treatment (Supplementary Fig.-S2A). Here, RARA is linked to acute promyelocytic leukemia.