In addition, we also found that Slc38a6+/- mice displayed ET-like tremors (Supplementary Videos 8 and 9) and exhibited significant morphological, electrophysiological or molecular alterations similar to those of Slc38a6-/- mice (Supplementary Notes and Supplementary Fig. 10a‒k), phenocopying the behavioral and neurological symptoms observed in ET. The gene discussed is SLC38A6; the disease is essential thrombocythemia.