Indeed, gene duplication events involving 17p13.1 (harboring SLC13A5), 3q25.31 (harboring AT-1), and 2p13.1 (harboring both ATases) are all associated with autism spectrum disorder with intellectual disability and progeria-like dysmorphism (see National Organization for Rare Disorders database; see also [Francke, 1978; Fineman et al, 1983; Fryns et al, 1989; Sawyer et al, 1994; Rizzu et al, 1997; Ounap et al, 2005; Krumm et al, 2013; Poultney et al, 2013; Carvalho et al, 2014; Mooneyham et al, 2014; Krumm et al, 2015]). The gene discussed is SLC13A5; the disease is autism spectrum disorder.