We transduced OCI-Ly8 (Ly8) cells, a human DLBCL cell line, in which we previously knocked out endogenous P2RY8,28 and performed three parallel screens: receptor surface expression (using the OX56 N-terminal tag33), cell migration, and proliferation (Figures 1A and S1A). The gene discussed is P2RY8; the disease is diffuse large B-cell lymphoma.