In conclusion, the pre-treatment MRD level, presence of neutropenia on day 7, CRP, ferritin concentration, APTT, and IL-6 levels exceeding 150 pg/mL were incorporated into the multivariate predictive model, with a prognostic nomogram subsequently developed on the basis of these significant parameters (Table 4; Fig. 3). The gene discussed is CRP; the disease is Decreased total neutrophil count.