TARDBP and amyotrophic lateral sclerosis: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting both upper and lower motor neurones, characterised by intracytoplasmic inclusions of transactivation response DNA‐binding protein of 43 kDa (TDP‐43), typically found in neurones and oligodendroglia [1, 2, 3, 4].