YAP1 and cytomegalovirus infection: The YAP1–TEAD complex exerts its activity by binding to enhancers of genes involved in extracellular matrix organization, actin cytoskeleton organization, and cell adhesion (Rausch and Hansen, 2020; Stein et al., 2015), all of which are pathways for which we see significantly altered gene expression levels subsequent to HCMV infection (Figure 5B).