Feeding mice with Prohep (a mixture of Lactobacillus rhamnosus GG, Escherichia coli Nissle 1917 and heat-inactivated VSL#3 in 1:1:1) reduced the production of TH17 cells (producing IL-17), upregulated anti-inflammatory Tregs, and downregulated genes responsible for angiogenesis, subsequently shrinking the tumor significantly (251). Here, IL17A is linked to neoplasm.