Regarding ischemic stroke, it has been suggested that bee venom toxins may cause hemolysis and endothelial damage, leading to the release of tissue thromboplastins and potentially promoting a state of disseminated intravascular coagulation (DIC), with blood vessel occlusion by fibrin thrombi (Jain et al., 2012). The gene discussed is F3; the disease is Disseminated intravascular coagulation.