Furthermore, the hematoxylin and eosin (H&E)-staining results indicated that the lung slices of the mice treated with Doxy@CaCO3-PEG and Tet-HER1-CAR-T cells presented no obvious tumor nodules on Day 14, whereas the lung slices of the mice subjected to the other two treatments presented obvious tumor nodules (Fig. 5H). The gene discussed is EGFR; the disease is neoplasm.