Using case T6 (HGSC) as an example, the object classifier is able to distinguish epithelial (primarily tumor) cells (Fig. 1A, B beige) from stromal cells using DAPI-nuclear features, with acceptable performance (by comparing to the H&E image, Fig. 1C); where stromal cells (Fig. 1A, B gray) are defined as remainder of cells in the stroma that are not CD8+ T cells or TIM3+ (presumed) macrophages. Here, CD8A is linked to neoplasm.