The expression of SGLT-2 in the renal cortex has been well-established in the literature.[20] Wang et al found that the expression of mRNA and SGLT-2 protein was higher in the kidney biopsy of patients with diabetic nephropathy compared to diabetic mice.[21] Although the same kind of expression seems to occur in the eye, there is still limited knowledge in this regard. The gene discussed is SLC5A2; the disease is diabetic kidney disease.