GPX4 and cardiomyopathy: Furthermore, ferroptosis, triggered byinhibition of glutathione peroxidase 4 (GPX4), and programmed necrosis, mediatedby the RIPK3–MLKL (receptor-interacting serine/threonine-protein kinase3‌‌-mixed lineage kinase domain-like protein‌) pathway, play dominant roles inischemic cardiomyopathy [49].