These derivatives were more cytotoxic than natural curcumin and were especially effective at inhibiting P‐glycoprotein (P‐gp), helping to overcome multidrug resistance in leukemia cells (Anuchapreeda et al. 2006c; Feriotto et al. 2023; Lopes‐Rodrigues et al. 2017; Lozada‐García et al. 2017). This evidence concerns the gene PGP and leukemia.