In addition, its genetic targets are focused on HCC-related pathways, such as PI3K/Akt, AMPK, apoptosis and cancer pathways (In vivo, mice, p.o., 0.072–1.404 kg/d, Saline (negative control); OXA (positive control)) (Zhou et al., 2024). The gene discussed is PIK3CA; the disease is hepatocellular carcinoma.