Additionally, studies have found that Salvia chinensis Benth suppresses Wnt/β-catenin activity by modulating Wnt1 to reduce β-catenin transcription in HCC cells, impeding the in vitro proliferation of PLC cells and obstructing the cell cycle (In vivo, Mice, p. o., 100 mg/kg/d, 5 weeks). Here, WNT1 is linked to hepatocellular carcinoma.