Conversely, Trajectory 4 captured late T1/alarmin‐driven inflammatory processes utilized by COVID‐19, demonstrating significantly increased IFNγ (log2FC 0.287, FDR adjusted p = 2.6e‐03) and IL‐33 responses (log2FC 0.218, FDR adjusted p = 4.6e‐03) compared to healthy MCs in late pseudotime phases (Figure S13B). This evidence concerns the gene IL33 and COVID-19.