We found significantly higher polygenic scores for T2D, fasting glucose, fasting insulin and waist–hip ratio in HNF-MODY patients compared with non-diabetic controls (0.09–0.42 s.d. increase, all P < 0.005) but no enrichment for T1D PGS (Fig. 1a). The gene discussed is INS; the disease is type 2 diabetes mellitus.