SOD1 and cancer: In cancer, for instance, the up-regulation of SOD enzymes tocontrol oxidative stress, thus, to avoid cell proliferation, seemsnot to be coupled with up-regulation of levels of peroxide-removingenzymes, resulting in turn in increased peroxide levels., Although the generation of H2O2 contributesto the anticancer activity, the accumulated H2O2 is also used by cancer cells for their proliferation. It is thus becoming evident that the developmentof an antioxidant system must be based on a combination of scavengerscapable of suppressing both the superoxide radical and hydrogen peroxide.