AM52.1CAR T cells produced pro-inflammatory cytokines, including macrophage inflammatory protein 1 beta (MIP-1β), interleukin (IL-8), interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), and IL-13, in response to STn-positive cancer cells (Figure 3F and S4F). The gene discussed is TNF; the disease is cancer.