AT binding to a murine cell line derived from a tumor that developed in mice with p53 deletion combined with a doxycycline-inducible mutant KRasG12D (iKRAS) (55) showed an increase in staining upon induction of KRAS expression with doxycycline (Supplemental Figure 5C), suggesting a link between KRAS status and HSAT expression as previously described for several HS proteoglycans (33). The gene discussed is KRAS; the disease is neoplasm.