In addition, treatment with outer membrane vesicles from P.g. significantly increased tumor volume induced by SCC-9 cells injected subcutaneously into the right flank, as well as cell proliferation (Ki-67) and expression of EMT markers such as N-cadherin, Vimentin, and MMP9, while reducing E-cadherin expression. The gene discussed is MKI67; the disease is neoplasm.