Univariate analysis showed that AFP level ≥ 60 ng/mL (p < 0.001), DCP value ≥ 100 mAU/mL (p = 0.016), tumor size ≥ 30 mm (p = 0.003), peCTC ≥ 5 (p < 0.001), and poCTC ≥ 5 (p < 0.001) were associated with microscopic PVI. The gene discussed is AFP; the disease is neoplasm.