Cluster 6 was characterized by the expression of the IFN-γ–induced genes Ifitm1, Ifitm2, and Ifitm3, which have been reported to be associated with inflammatory bowel diseases (Wu et al., 2007), alongside with the integrin Itgb1 (Pawlak et al., 2022). Here, IFITM2 is linked to inflammatory bowel disease.