For instance, angiotensin II type 1 receptor (AT1R) blockers (ARBs) and calcium channel blockers might be candidates for Alzheimer's disease;22 the loop diuretic bumetanide produced beneficial effects in cases of autism, schizophrenia, and temporal lobe epilepsy;23 and β blockers knowingly improve anxiety symptoms.24 The gene discussed is AGTR1; the disease is early-onset autosomal dominant Alzheimer disease.