Consistent with our previous studies (17), the percentages of IL-22+CD4+ or CD8+ T cells were higher in SR-Gut-aGVHD as compared with non-SR-GVHD colon sections, and there were more CD8+ than CD4+ among the IL-22+ T cells (Figure 1, C–F). The gene discussed is CD4; the disease is graft versus host disease.