The MR analysis using the IVW method demonstrated suggestive evidence of causality of 8 circulating inflammatory proteins on IPF (Figure 3): CCL11 (OR = 1.377, 95% CI [1.040, 1.822], p = 0.025), CXCL6 (OR = 1.725, 95% CI [1.044, 2.851], p = 0.033), CXCL9 (OR = 1.576, 95% CI [1.052, 2.362], p = 0.028), CCL8 (OR = 1.322, 95% CI [1.076, 1.623], p = 0.008), CCL7 (OR = 1.488, 95% CI [1.083, 2.044], p = 0.014), NRTN (OR = 1.395, 95% CI [1.011, 1.924], p = 0.043), STAMPB (OR = 1.771, 95% CI [1.013, 3.096], p = 0.045), TGFa (OR = 1.581, 95% CI [1.083, 2.310], p = 0.018). Here, CCL8 is linked to idiopathic pulmonary fibrosis.