MTOR and hepatocellular carcinoma: In this investigation exogenous hydrogen sulfide donor sodium hydrosulfide (NaHS) was administered to HCC cells, demonstrating that NaHS effectively downregulated phosphorylated-phosphatidylinositol 3-kinase (p-PI3K), phosphorylated-protein kinase B (p-Akt), and mammalian target of rapamycin (mTOR) expression in the PI3K/Akt/mTOR signaling pathway.