In case of lung cancer, various targets like HER2, EGFR, MAGE-A1, MUC1, mesothelin (MSLN), CEA, inactive Tyrosine-protein kinase transmembrane receptor ROR1, PD-L1, B7-H3 and Chemokine receptor CXC4 have been identified and clinical studies have already been performed. This evidence concerns the gene CD274 and lung cancer.