Intercellular transmissions are made possible when spike protein on the surface of infected cells interacts with hACE2 on the neighboring cells, mediated by the presence of transmembrane protease, serine 2 (TMPRSS2).5,6 These interactions cause fusions of infected cells with other host cells, leading to syncytia formation.6 Syncytia were proved to be found in lung tissues of early-stage COVID-19 patients.7 Bussani et al8 in their systematic analysis of COVID-19 patients report that post-mortem examination showed the presence of syncytia in 36 out of 41 patients. Here, TMPRSS2 is linked to COVID-19.