AKT1 and acute myeloid leukemia: Inhibiting TLR2 or Akt/mTOR signaling mitigated MDSC differentiation, suggesting a potential therapeutic strategy to counter MDSC‐mediated immune suppression in AML, highlighting the significance of EV‐associated palmitoylated proteins in disrupting leukemogenesis and improving immune responses, thereby enhancing antitumor immune responses and improving patient outcomes in acute myeloid leukemia [38], as illustrated in Table 1.