As illustrated in Table 2, patients in the recurrence group showed increased expression of TLR1, TLR6, and TLR8 receptors, so that NOD‐like and TNF‐α signaling were increased, and they are commonly associated with promoting a protective CML microenvironment [22]. Here, TLR6 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.