NRG1 and major depressive disorder: 2021, Rao et al. 2017, W. Wang et al. 2020, Xu et al. 2020). Its expression in the medial prefrontal cortex is critical for stress resilience, and deficiencies are associated with depression‐like phenotypes. NRG1 dysregulation has also been linked to altered dendritic morphology and neuroinflammatory responses in SZ, with implications for BD and PTSD (Chohan et al. 2014, Clarke et al. 2019, Taylor et al. 2011).