It was indicated that the DEGs between T2DM and CS were bound up with ion transport, immune response, and infection, which was in accord with published researches.[23] KEGG analysis showed that the DEGs were enriched in S aureus infection, NF-kappa B signaling pathway, fluid shear stress and atherosclerosis, transcriptional misregulation in cancer, amebiasis, c-type lectin receptor signaling pathway, and sulfur metabolism, mostly related to immunity, inflammation, and infection. The gene discussed is CLEC4D; the disease is atherosclerosis.