ROC curves based on the risk model (Fig. 3), demonstrated that PSRC1 (AUC: 0.722, 95% CI 0.66–0.787), CELSR2 (AUC: 0.657, 95% CI 0.576–0.732), and MYBPHL (AUC: 0.677, 95% CI 0.609–0.742) have high diagnostic value for CHD and MI. The gene discussed is CELSR2; the disease is coronary artery disorder.