Supporting this, animal models and patient samples have demonstrated upregulation of M2 macrophage‐related genes (Arg1, Ym1) and cytokines (IL‐10, TGF‐β) at lesion sites, with their mRNA levels positively correlated with cyst diameter and growth rate (De Biase et al. 2023). Here, TGFB1 is linked to cyst.