chIRAP overexpression significantly inhibited the proliferation of VSV-EGFP, NDV-rL-EGFP and NDV-Na-EGFP, and reduced viral infection 87.3-fold, 6.87-fold, and 24.84-fold, respectively (Fig 3D), and inhibited the expression level of H9N2 IAV HA protein (Fig 3E), suggesting it also has an inhibitory effect on H9N2 IAV. This evidence concerns the gene RELN and viral infectious disease.