Pathway enrichment analysis of SLAMF5-regulated genes revealed strong associations with immune-related and neuroinflammatory pathways, Th1 and Th2 differentiation, interferon signaling, agranulocyte adhesion and diapedesis, IRF activation, neuroinflammation signaling, iNOS signaling, and pathways implicated in the pathogenesis of MS. Here, CD84 is linked to myeloid sarcoma.