IFNG and leishmaniasis: In a study involving BALB/c mice, the in vivo administration of truncated and liposomal EF1-α was observed to trigger a Th1 immune response, marked by elevated levels of IFN-γ, IL-12, and TNF-α with concurrent suppression of IL-4, IL-10, and TGF-β levels, ensuring protective response in leishmaniasis [53].