TSLPR was also found to be highly expressed in inflammatory infiltrate (composed of eosinophils, mast cells, and histiocytes) and epithelial cells in patients with CRSwNP and CRSsNP compared with tissue from healthy controls, with no significant difference between patients with CRSwNP and those with CRSsNP [40]. This evidence concerns the gene CRLF2 and chronic rhinosinusitis without nasal polyps.