Serum miR-1 levels were inversely correlated with tissue eosinophilia in samples from patients with CRSwNP, and miR-1 recruited TSLP (and P-selectin, CCL26 [eotaxin-3], and thrombopoietin receptor) to the RNA-induced silencing complex and downregulated these genes [92]. The gene discussed is TSLP; the disease is Increased total eosinophil count.