For 6 prioritized genes in PCa, GLOD4 (GSE46602: P-value <0.001; GSE70768: P-value <0.05), MRPL24 (GSE46602: P-value <0.001; GSE70768: P-value <0.001), and PUS1 (GSE46602: P-value <0.001; GSE70768: P-value <0.001) were cross-validated in two RNA-sequencing datasets (Figure 4E). The gene discussed is PUS1; the disease is posterior cortical atrophy.