PFKFB3 and hepatocellular carcinoma: qPCR results revealed an induction on the transcription of solute carrier family 2 member 1 (SLC2A1), HK2, and PFKFB3 genes by G1896A mutation, and western blotting results showed that PFKFB3 was remarkably induced by G1896A mutation in HCC cells (Figure 4A,B).