However, sulforaphane does not selectively target NLRP3 inflammasome [30]; cardamonin inhibits NLPR3 inflammasome activation by agitating aryl hydrocarbon receptor [31], but it can lead to adverse reactions including liver injury and intestinal obstruction [32]; BHB blocks NLRP3 inflammasome activation through decreasing K+ efflux [8], but it also halts NF‐κB signaling transduction [33]. The gene discussed is AHR; the disease is intestinal obstruction.