Although these associations are correlative, they are consistent with findings in cancer models, where Peak1—a non-receptor tyrosine kinase associated with the cytoskeleton—mediates signaling crosstalk between transforming growth factor beta receptors and integrin/Src/MAPK pathways (Agajanian et al., 2015; Wang et al., 2010). The gene discussed is NTRK1; the disease is cancer.