Mean fibrinogen levels were markedly higher in the AECOPD patients (mean±SD: 577.23±112.12 mg/dL) compared to stable COPD (391.2±87.15 mg/dL; p<0.0001), and similar trends were seen for D-dimer (0.93±0.28 vs. 0.46±0.19 μg/mL) and vWF (159.2±36.42 vs. 116.6±30.23 IU/dL). The gene discussed is VWF; the disease is chronic obstructive pulmonary disease.