CXCL1 and Alzheimer disease: In addition, 7-methoxyisoflavone has been reported to significantly suppress CXCL1, CXCL2, and CXCL3 expression in both FITC- and oxazolone-induced AD models, which was associated with reduced neutrophil infiltration and attenuated skin erythema and edema (Dong et al., 2022).