For example, lncRNA LINC00337 (Lnc-LBCS) has been reported to suppress bladder cancer “stemness” by binding to the chromatin modifier EZH2 and the RNA-binding protein hnRNPK, forming a complex that represses the stem cell gene SOX2 (Chen et al., 2019). This evidence concerns the gene EZH2 and urinary bladder cancer.