JLP, a (JNK interacting protein) family scaffold protein for MAPK pathway (Dhanasekaran et al., 2007), negatively regulates peritoneal fibrosis by modulating TGF-β1/Smad signalling pathway, EMT, autophagy, and apoptosis (Tian et al., 2022). This evidence concerns the gene SPAG9 and Peritoneal Fibrosis.