To evaluate the effects of upregulated expression of TIMM8A or TIMM13 on the biological behaviors of lung cancer cells, two distinct siRNAs targeting either TIMM8A (siTIMM8A-66 and siTIMM8A-228) or TIMM13 (siTIMM13-118 and siTIMM13-215) were employed to silence TIMM8A or TIMM13 in two lung cancer cell lines, A549 and PC-9. This evidence concerns the gene TIMM8A and lung cancer.