Among these, the CCND1/CDK6 complex, a key regulator of lung cancer cell growth, emerged as a potential mediator of TIMM8A-TIMM13 complex oncogenic mechanisms, as TIMM13 or TIMM8A knockdown significantly suppressed CCND1 and CDK6 expression, as confirmed by RNA sequencing data and immunoblotting results. Here, CDK6 is linked to lung cancer.