In the context of the B16 melanoma model, utilizing syngeneic mice of the C57BL/6 line, the studies demonstrated the binding of FAP-IL2v to FAPα in the tumor stroma, leading to the activation of interleukin-2 receptor beta-gamma chain complex (IL-2Rβγ) on effector cells, resulting in a substantial reduction in tumor volume. Here, FAP is linked to neoplasm.